Human age-related cataracts: Epigenetic suppression of the nuclear factor erythroid 2-related factor 2-mediated antioxidant system

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Human age‑related cataracts: epigenetic suppression of the nuclear factor erythroid 2‑related factor 2‑mediated antioxidant system.

Human aging is a multifactorial process. The most prominent effects of aging include visual impairments, particularly age‑related cataracts (ARC). Several studies have reported that oxidative stress and failure of the antioxidant system are the major factors contributing to lens oxidation. The present study focused on the nuclear factor erythroid 2‑related factor 2 (Nrf2)/kelch‑like ECH‑associa...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2014

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2014.2849